Have you ever wondered why some people find it much easier to quit than others?
New research shows that the vulnerability to addiction to snuff our genes involved.
A study by the Montreal Neurological Institute and Hospital, McGill University-dependent in Canada, shows that people with a fast metabolism of nicotine (genetically determined), the brain responds to evidence that smoking remember, as do people smoking cigarettes or, much more intensely than in those with a slow metabolism of nicotine.
In other words, the rate of metabolism of nicotine is to significantly affect the brain’s response to those signals.
Previous research had shown that greater reactivity evidence remember smoking predicts less success when trying to quit smoking, and that those signals reminder of snuff in the environment stimulate increased consumption of nicotine in animals and people.
This new finding, in a research team led by Dr. Alain Dagher, can lay the groundwork for programs to quit smoking are tailored to the individual in a better way, based on the genes of the subject.
Future research could focus on improving methods to quit smoking, by way of tailor treatment to different genetic types of smokers. A possible strategy would be to measure the rate of metabolism of nicotine as part of the therapeutic decisions. For example, devoting special attention to the risk of relapse caused by signals present in the environment may not serve much use to people who have a slow metabolism of nicotine, which is more likely to benefit from cholinergic drugs acting, such as nicotine patches, which agrees with the findings of previous clinical trials.
By contrast, the use of therapies that do not use nicotine and that are more directly aimed at reducing the desire to smoke can help people to fast metabolism, as demonstrated with bupropion, an antidepressant that has been used in smoking cessation treatments.